Chlorhexidine Gluconate + Sodium Fluoride + Zinc Chloride UsesChlorhexidine Gluconate+Sodium Fluoride+Zinc Chloride is used in the treatment of mouth infection.How Chlorhexidine Gluconate + Sodium Fluoride + Zinc Chloride worksChlorhexidine Gluconate + Sodium Fluoride + Zinc Chloride is a combination of three medicines: Chlorhexidine Gluconate , Sodium Fluoride and Zinc Chloride. Chlorhexidine Gluconate is an antiseptic. It works by binding to the surface of teeth, inner cheeks and gums. This kills the infectious microorganisms that cause gum disease, ulcers and other mouth infections. Sodium Fluoride works by making the teeth stronger and preventing decay (cavity) caused by bacteria. Zinc Chloride has antiseptic and astringent action.